Physical Properties | | | |
Molecular Weight: 426.513 g/mol | logS: -8.39739 | SlogP: 3.8841 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0344184 | Sterimol/B1: 2.56111 | Sterimol/B2: 3.02976 | Sterimol/B3: 4.18282 |
Sterimol/B4: 8.65765 | Sterimol/L: 22.1846 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 709.162 | Positive charged surface: 429.057 | Negative charged surface: 280.105 | Volume: 401 |
Hydrophobic surface: 512.542 | Hydrophilic surface: 196.62 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |