Physical Properties | | | |
Molecular Weight: 415.021 g/mol | logS: -6.91152 | SlogP: 6.2292 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.123288 | Sterimol/B1: 2.33435 | Sterimol/B2: 4.50771 | Sterimol/B3: 4.64271 |
Sterimol/B4: 9.74686 | Sterimol/L: 17.9596 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 710.629 | Positive charged surface: 457.764 | Negative charged surface: 252.864 | Volume: 425.125 |
Hydrophobic surface: 576.84 | Hydrophilic surface: 133.789 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |