Physical Properties | | | |
Molecular Weight: 462.549 g/mol | logS: -8.06738 | SlogP: 6.14102 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.111046 | Sterimol/B1: 2.08525 | Sterimol/B2: 2.97952 | Sterimol/B3: 5.67735 |
Sterimol/B4: 11.7555 | Sterimol/L: 17.9814 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 780.024 | Positive charged surface: 443.242 | Negative charged surface: 336.782 | Volume: 461.75 |
Hydrophobic surface: 715.726 | Hydrophilic surface: 64.298 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |