Physical Properties | | | |
Molecular Weight: 381.263 g/mol | logS: -5.06163 | SlogP: 4.3251 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0412854 | Sterimol/B1: 2.32051 | Sterimol/B2: 3.44315 | Sterimol/B3: 4.29467 |
Sterimol/B4: 8.49131 | Sterimol/L: 21.3488 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 650.247 | Positive charged surface: 331.311 | Negative charged surface: 318.936 | Volume: 337.25 |
Hydrophobic surface: 519.561 | Hydrophilic surface: 130.686 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |