Physical Properties | | | |
Molecular Weight: 394.455 g/mol | logS: -2.90547 | SlogP: 3.3701 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.115899 | Sterimol/B1: 3.52293 | Sterimol/B2: 4.71122 | Sterimol/B3: 4.85531 |
Sterimol/B4: 6.05379 | Sterimol/L: 16.9706 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 614.331 | Positive charged surface: 394.095 | Negative charged surface: 220.235 | Volume: 360.25 |
Hydrophobic surface: 458.676 | Hydrophilic surface: 155.655 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |