Physical Properties | | | |
Molecular Weight: 460.327 g/mol | logS: -5.94516 | SlogP: 3.9922 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.223179 | Sterimol/B1: 2.79632 | Sterimol/B2: 4.73501 | Sterimol/B3: 4.89279 |
Sterimol/B4: 6.4824 | Sterimol/L: 17.3513 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 612.009 | Positive charged surface: 308.074 | Negative charged surface: 303.935 | Volume: 382.875 |
Hydrophobic surface: 523.003 | Hydrophilic surface: 89.006 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |