Physical Properties | | | |
Molecular Weight: 375.859 g/mol | logS: -5.04453 | SlogP: 5.59422 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.164782 | Sterimol/B1: 2.48839 | Sterimol/B2: 4.86105 | Sterimol/B3: 6.05576 |
Sterimol/B4: 7.42653 | Sterimol/L: 16.5294 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 623.404 | Positive charged surface: 337.565 | Negative charged surface: 280.271 | Volume: 351.25 |
Hydrophobic surface: 551.752 | Hydrophilic surface: 71.652 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |