Physical Properties | | | |
Molecular Weight: 406.869 g/mol | logS: -4.84045 | SlogP: 4.09637 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.055074 | Sterimol/B1: 3.1454 | Sterimol/B2: 3.28244 | Sterimol/B3: 4.71441 |
Sterimol/B4: 10.5132 | Sterimol/L: 18.1403 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 663.644 | Positive charged surface: 351.6 | Negative charged surface: 312.044 | Volume: 374.25 |
Hydrophobic surface: 581.016 | Hydrophilic surface: 82.628 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |