Physical Properties | | | |
Molecular Weight: 480.495 g/mol | logS: -6.45005 | SlogP: 6.1534 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.212341 | Sterimol/B1: 4.1809 | Sterimol/B2: 4.32902 | Sterimol/B3: 5.78416 |
Sterimol/B4: 8.79319 | Sterimol/L: 17.7587 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 751.351 | Positive charged surface: 410.752 | Negative charged surface: 340.599 | Volume: 443.125 |
Hydrophobic surface: 628.028 | Hydrophilic surface: 123.323 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |