Physical Properties | | | |
Molecular Weight: 415.276 g/mol | logS: -6.89385 | SlogP: 5.19 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0325343 | Sterimol/B1: 3.54844 | Sterimol/B2: 3.67646 | Sterimol/B3: 4.40214 |
Sterimol/B4: 6.20182 | Sterimol/L: 21.604 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 669.732 | Positive charged surface: 310.66 | Negative charged surface: 359.072 | Volume: 363.625 |
Hydrophobic surface: 544.117 | Hydrophilic surface: 125.615 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |