Physical Properties | | | |
Molecular Weight: 384.459 g/mol | logS: -7.86906 | SlogP: 5.28128 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.293034 | Sterimol/B1: 1.969 | Sterimol/B2: 3.92543 | Sterimol/B3: 7.32674 |
Sterimol/B4: 8.89734 | Sterimol/L: 14.6601 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 617.453 | Positive charged surface: 344.81 | Negative charged surface: 259.993 | Volume: 354.625 |
Hydrophobic surface: 495.662 | Hydrophilic surface: 121.791 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |