Physical Properties | | | |
Molecular Weight: 397.434 g/mol | logS: -6.42003 | SlogP: 4.55002 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.020929 | Sterimol/B1: 2.40418 | Sterimol/B2: 3.34228 | Sterimol/B3: 3.99466 |
Sterimol/B4: 9.43532 | Sterimol/L: 19.5218 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 677.82 | Positive charged surface: 370.298 | Negative charged surface: 301.676 | Volume: 377.125 |
Hydrophobic surface: 547.113 | Hydrophilic surface: 130.707 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |