Physical Properties | | | |
Molecular Weight: 387.407 g/mol | logS: -4.1843 | SlogP: 3.94302 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.133459 | Sterimol/B1: 2.17519 | Sterimol/B2: 6.09047 | Sterimol/B3: 6.58169 |
Sterimol/B4: 7.47593 | Sterimol/L: 17.0178 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 690.919 | Positive charged surface: 435.044 | Negative charged surface: 250.339 | Volume: 360.875 |
Hydrophobic surface: 590.86 | Hydrophilic surface: 100.059 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |