Physical Properties | | | |
Molecular Weight: 408.396 g/mol | logS: -5.64997 | SlogP: 3.80531 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0775642 | Sterimol/B1: 2.02874 | Sterimol/B2: 3.69016 | Sterimol/B3: 4.21733 |
Sterimol/B4: 8.30886 | Sterimol/L: 19.7163 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 653.824 | Positive charged surface: 319.736 | Negative charged surface: 334.088 | Volume: 365.75 |
Hydrophobic surface: 433.457 | Hydrophilic surface: 220.367 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |