Physical Properties | | | |
Molecular Weight: 415.901 g/mol | logS: -5.28326 | SlogP: 3.053 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0508876 | Sterimol/B1: 2.46008 | Sterimol/B2: 3.39335 | Sterimol/B3: 4.91042 |
Sterimol/B4: 6.60219 | Sterimol/L: 20.7421 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 644.384 | Positive charged surface: 315.74 | Negative charged surface: 328.644 | Volume: 361.125 |
Hydrophobic surface: 520.287 | Hydrophilic surface: 124.097 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |