Physical Properties | | | |
Molecular Weight: 415.441 g/mol | logS: -3.64631 | SlogP: 0.437 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.163897 | Sterimol/B1: 2.19956 | Sterimol/B2: 4.24953 | Sterimol/B3: 5.70303 |
Sterimol/B4: 10.0063 | Sterimol/L: 16.8904 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 674.009 | Positive charged surface: 456.426 | Negative charged surface: 217.582 | Volume: 387.125 |
Hydrophobic surface: 490.607 | Hydrophilic surface: 183.402 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |