Physical Properties | | | |
Molecular Weight: 409.934 g/mol | logS: -5.13721 | SlogP: 4.33356 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.237599 | Sterimol/B1: 2.1511 | Sterimol/B2: 4.16259 | Sterimol/B3: 5.65797 |
Sterimol/B4: 9.60614 | Sterimol/L: 15.1605 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 612.937 | Positive charged surface: 349.818 | Negative charged surface: 263.119 | Volume: 372.375 |
Hydrophobic surface: 525.248 | Hydrophilic surface: 87.689 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |