Physical Properties | | | |
Molecular Weight: 400.76 g/mol | logS: -5.23465 | SlogP: 3.59587 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0467593 | Sterimol/B1: 2.15034 | Sterimol/B2: 4.3994 | Sterimol/B3: 4.81975 |
Sterimol/B4: 4.92132 | Sterimol/L: 20.04 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 602.926 | Positive charged surface: 229.247 | Negative charged surface: 373.679 | Volume: 326.875 |
Hydrophobic surface: 394.424 | Hydrophilic surface: 208.502 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |