Physical Properties | | | |
Molecular Weight: 381.375 g/mol | logS: -3.71853 | SlogP: 3.4201 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0558591 | Sterimol/B1: 2.53889 | Sterimol/B2: 3.19951 | Sterimol/B3: 4.01568 |
Sterimol/B4: 8.14798 | Sterimol/L: 17.9882 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 593.083 | Positive charged surface: 366.304 | Negative charged surface: 226.779 | Volume: 310.375 |
Hydrophobic surface: 347.783 | Hydrophilic surface: 245.3 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |