Physical Properties | | | |
Molecular Weight: 402.881 g/mol | logS: -6.27422 | SlogP: 5.49032 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.109624 | Sterimol/B1: 2.63057 | Sterimol/B2: 3.41275 | Sterimol/B3: 4.96392 |
Sterimol/B4: 7.62744 | Sterimol/L: 16.1818 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 603.518 | Positive charged surface: 324.636 | Negative charged surface: 275.03 | Volume: 374.375 |
Hydrophobic surface: 525.102 | Hydrophilic surface: 78.416 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |