Physical Properties | | | |
Molecular Weight: 405.821 g/mol | logS: -6.25389 | SlogP: 2.8997 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0525889 | Sterimol/B1: 2.3083 | Sterimol/B2: 2.45879 | Sterimol/B3: 5.37559 |
Sterimol/B4: 8.12642 | Sterimol/L: 18.8862 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 646.481 | Positive charged surface: 309.689 | Negative charged surface: 336.792 | Volume: 359 |
Hydrophobic surface: 463.411 | Hydrophilic surface: 183.07 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |