Physical Properties | | | |
Molecular Weight: 381.796 g/mol | logS: -3.9773 | SlogP: 4.4477 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.172848 | Sterimol/B1: 3.52685 | Sterimol/B2: 3.63032 | Sterimol/B3: 4.86186 |
Sterimol/B4: 9.46169 | Sterimol/L: 14.0649 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 603.164 | Positive charged surface: 337.848 | Negative charged surface: 265.316 | Volume: 340.125 |
Hydrophobic surface: 483.581 | Hydrophilic surface: 119.583 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |