Physical Properties | | | |
Molecular Weight: 377.407 g/mol | logS: -5.58862 | SlogP: 3.4935 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0443828 | Sterimol/B1: 2.49373 | Sterimol/B2: 3.32681 | Sterimol/B3: 4.13847 |
Sterimol/B4: 6.45326 | Sterimol/L: 19.4812 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 626.412 | Positive charged surface: 420.67 | Negative charged surface: 205.742 | Volume: 336.75 |
Hydrophobic surface: 410.173 | Hydrophilic surface: 216.239 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |