Physical Properties | | | |
Molecular Weight: 409.449 g/mol | logS: -5.76655 | SlogP: 4.9025 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.388576 | Sterimol/B1: 3.22474 | Sterimol/B2: 3.46553 | Sterimol/B3: 7.80514 |
Sterimol/B4: 10.524 | Sterimol/L: 13.0123 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 695.383 | Positive charged surface: 419.542 | Negative charged surface: 275.841 | Volume: 388.875 |
Hydrophobic surface: 538.873 | Hydrophilic surface: 156.51 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |