Physical Properties | | | |
Molecular Weight: 383.432 g/mol | logS: -4.55682 | SlogP: 2.1175 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.109604 | Sterimol/B1: 4.505 | Sterimol/B2: 4.69326 | Sterimol/B3: 5.77756 |
Sterimol/B4: 6.03137 | Sterimol/L: 16.9153 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 618.959 | Positive charged surface: 340.292 | Negative charged surface: 244.436 | Volume: 339 |
Hydrophobic surface: 453.815 | Hydrophilic surface: 165.144 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |