Physical Properties | | | |
Molecular Weight: 412.445 g/mol | logS: -5.79425 | SlogP: 3.8966 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0886316 | Sterimol/B1: 3.28813 | Sterimol/B2: 4.19139 | Sterimol/B3: 4.83956 |
Sterimol/B4: 7.66611 | Sterimol/L: 17.613 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 636.018 | Positive charged surface: 358.643 | Negative charged surface: 277.375 | Volume: 384.75 |
Hydrophobic surface: 488.38 | Hydrophilic surface: 147.638 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |