Physical Properties | | | |
Molecular Weight: 397.381 g/mol | logS: -6.38353 | SlogP: 3.9556 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0386575 | Sterimol/B1: 2.03508 | Sterimol/B2: 2.98363 | Sterimol/B3: 5.0076 |
Sterimol/B4: 6.34002 | Sterimol/L: 17.617 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 587.465 | Positive charged surface: 305.16 | Negative charged surface: 282.305 | Volume: 318.625 |
Hydrophobic surface: 313.859 | Hydrophilic surface: 273.606 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |