Physical Properties | | | |
Molecular Weight: 418.493 g/mol | logS: -5.39182 | SlogP: 4.3985 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0400831 | Sterimol/B1: 3.40627 | Sterimol/B2: 3.43963 | Sterimol/B3: 3.63394 |
Sterimol/B4: 12.1891 | Sterimol/L: 17.7492 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 713.3 | Positive charged surface: 457.716 | Negative charged surface: 255.585 | Volume: 410.5 |
Hydrophobic surface: 664.344 | Hydrophilic surface: 48.956 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |