Physical Properties | | | |
Molecular Weight: 425.481 g/mol | logS: -5.56197 | SlogP: 4.1002 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0930256 | Sterimol/B1: 2.74628 | Sterimol/B2: 4.14359 | Sterimol/B3: 5.24607 |
Sterimol/B4: 7.61614 | Sterimol/L: 20.1681 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 744.206 | Positive charged surface: 450.819 | Negative charged surface: 283.827 | Volume: 406.5 |
Hydrophobic surface: 534.62 | Hydrophilic surface: 209.586 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |