Physical Properties | | | |
Molecular Weight: 394.431 g/mol | logS: -4.60108 | SlogP: 3.02527 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0719339 | Sterimol/B1: 2.45932 | Sterimol/B2: 3.01348 | Sterimol/B3: 4.60925 |
Sterimol/B4: 9.48522 | Sterimol/L: 18.127 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 680.184 | Positive charged surface: 400.581 | Negative charged surface: 279.603 | Volume: 372.25 |
Hydrophobic surface: 548.917 | Hydrophilic surface: 131.267 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |