Physical Properties | | | |
Molecular Weight: 401.466 g/mol | logS: -5.40379 | SlogP: 3.46084 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0652525 | Sterimol/B1: 3.11348 | Sterimol/B2: 3.85821 | Sterimol/B3: 4.69321 |
Sterimol/B4: 9.91014 | Sterimol/L: 18.3653 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 715.13 | Positive charged surface: 404.946 | Negative charged surface: 304.984 | Volume: 389.625 |
Hydrophobic surface: 595.839 | Hydrophilic surface: 119.291 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |