Physical Properties | | | |
Molecular Weight: 426.577 g/mol | logS: -5.31417 | SlogP: 3.22537 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0696571 | Sterimol/B1: 2.17538 | Sterimol/B2: 5.12326 | Sterimol/B3: 6.20544 |
Sterimol/B4: 6.33959 | Sterimol/L: 19.6905 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 713.078 | Positive charged surface: 565.043 | Negative charged surface: 148.035 | Volume: 433.625 |
Hydrophobic surface: 603.762 | Hydrophilic surface: 109.316 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |