Physical Properties | | | |
Molecular Weight: 396.464 g/mol | logS: -3.01197 | SlogP: 1.3473 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0722913 | Sterimol/B1: 2.41654 | Sterimol/B2: 3.54097 | Sterimol/B3: 4.50024 |
Sterimol/B4: 9.83928 | Sterimol/L: 17.7645 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 674.843 | Positive charged surface: 417.239 | Negative charged surface: 257.604 | Volume: 360.75 |
Hydrophobic surface: 427.169 | Hydrophilic surface: 247.674 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |