Physical Properties | | | |
Molecular Weight: 408.43 g/mol | logS: -6.25244 | SlogP: 1.64367 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0798556 | Sterimol/B1: 3.46227 | Sterimol/B2: 3.95239 | Sterimol/B3: 4.7122 |
Sterimol/B4: 7.45792 | Sterimol/L: 17.2641 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 679.103 | Positive charged surface: 376.33 | Negative charged surface: 302.773 | Volume: 386.875 |
Hydrophobic surface: 456.149 | Hydrophilic surface: 222.954 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |