Physical Properties | | | |
Molecular Weight: 504.491 g/mol | logS: -6.70649 | SlogP: 3.5826 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.158637 | Sterimol/B1: 2.26071 | Sterimol/B2: 2.28232 | Sterimol/B3: 7.56471 |
Sterimol/B4: 14.076 | Sterimol/L: 19.5625 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 844.11 | Positive charged surface: 468.891 | Negative charged surface: 375.219 | Volume: 462.5 |
Hydrophobic surface: 711.209 | Hydrophilic surface: 132.901 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |