Physical Properties | | | |
Molecular Weight: 407.494 g/mol | logS: -4.51877 | SlogP: 3.61064 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0576048 | Sterimol/B1: 1.969 | Sterimol/B2: 3.50126 | Sterimol/B3: 4.40368 |
Sterimol/B4: 11.3121 | Sterimol/L: 18.3186 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 703.085 | Positive charged surface: 434.116 | Negative charged surface: 265.002 | Volume: 381.125 |
Hydrophobic surface: 583.312 | Hydrophilic surface: 119.773 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |