Physical Properties | | | |
Molecular Weight: 417.509 g/mol | logS: -5.12961 | SlogP: 3.75697 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.163452 | Sterimol/B1: 3.98536 | Sterimol/B2: 5.81346 | Sterimol/B3: 5.98348 |
Sterimol/B4: 6.68007 | Sterimol/L: 18.0639 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 698.477 | Positive charged surface: 473.339 | Negative charged surface: 219.878 | Volume: 407 |
Hydrophobic surface: 581.503 | Hydrophilic surface: 116.974 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |