Physical Properties | | | |
Molecular Weight: 402.495 g/mol | logS: -5.20097 | SlogP: 4.1999 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.107644 | Sterimol/B1: 2.11891 | Sterimol/B2: 4.08479 | Sterimol/B3: 4.17938 |
Sterimol/B4: 11.6867 | Sterimol/L: 14.098 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 654.67 | Positive charged surface: 341.718 | Negative charged surface: 312.952 | Volume: 354 |
Hydrophobic surface: 502.397 | Hydrophilic surface: 152.273 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |