Physical Properties | | | |
Molecular Weight: 417.51 g/mol | logS: -3.63524 | SlogP: 3.1732 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0628597 | Sterimol/B1: 2.66925 | Sterimol/B2: 3.11249 | Sterimol/B3: 5.20069 |
Sterimol/B4: 9.66321 | Sterimol/L: 18.3248 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 664.814 | Positive charged surface: 403.608 | Negative charged surface: 261.206 | Volume: 365.875 |
Hydrophobic surface: 531.558 | Hydrophilic surface: 133.256 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |