Physical Properties | | | |
Molecular Weight: 416.522 g/mol | logS: -5.27655 | SlogP: 4.2242 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0347017 | Sterimol/B1: 3.91005 | Sterimol/B2: 4.01928 | Sterimol/B3: 4.53855 |
Sterimol/B4: 7.04953 | Sterimol/L: 19.5609 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 675.992 | Positive charged surface: 364.236 | Negative charged surface: 311.756 | Volume: 369.125 |
Hydrophobic surface: 548.845 | Hydrophilic surface: 127.147 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |