Physical Properties | | | |
Molecular Weight: 400.907 g/mol | logS: -4.41426 | SlogP: 2.98312 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.033313 | Sterimol/B1: 2.51205 | Sterimol/B2: 2.68987 | Sterimol/B3: 4.23324 |
Sterimol/B4: 8.02817 | Sterimol/L: 17.8927 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 600.575 | Positive charged surface: 306.343 | Negative charged surface: 294.232 | Volume: 331.5 |
Hydrophobic surface: 494.376 | Hydrophilic surface: 106.199 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |