Physical Properties | | | |
Molecular Weight: 400.496 g/mol | logS: -2.35048 | SlogP: 1.2556 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.164811 | Sterimol/B1: 3.3196 | Sterimol/B2: 5.33241 | Sterimol/B3: 6.20209 |
Sterimol/B4: 7.02168 | Sterimol/L: 16.072 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 668.082 | Positive charged surface: 518.572 | Negative charged surface: 149.51 | Volume: 372.75 |
Hydrophobic surface: 540.961 | Hydrophilic surface: 127.121 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |