Physical Properties | | | |
Molecular Weight: 404.422 g/mol | logS: -5.61963 | SlogP: 2.86257 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0472057 | Sterimol/B1: 3.11514 | Sterimol/B2: 4.09177 | Sterimol/B3: 5.40945 |
Sterimol/B4: 6.80832 | Sterimol/L: 17.3735 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 619.037 | Positive charged surface: 353.173 | Negative charged surface: 265.864 | Volume: 378.375 |
Hydrophobic surface: 494.576 | Hydrophilic surface: 124.461 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |