Physical Properties | | | |
Molecular Weight: 399.898 g/mol | logS: -4.01116 | SlogP: 3.7479 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0299367 | Sterimol/B1: 2.40277 | Sterimol/B2: 3.22935 | Sterimol/B3: 3.30688 |
Sterimol/B4: 8.1205 | Sterimol/L: 21.5921 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 703.93 | Positive charged surface: 477.133 | Negative charged surface: 226.797 | Volume: 389.125 |
Hydrophobic surface: 610.857 | Hydrophilic surface: 93.073 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |