Physical Properties | | | |
Molecular Weight: 381.384 g/mol | logS: -3.79074 | SlogP: 2.6871 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.154329 | Sterimol/B1: 2.2011 | Sterimol/B2: 3.35813 | Sterimol/B3: 5.09609 |
Sterimol/B4: 10.9646 | Sterimol/L: 15.9252 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 624.11 | Positive charged surface: 383.604 | Negative charged surface: 240.506 | Volume: 349.125 |
Hydrophobic surface: 424.665 | Hydrophilic surface: 199.445 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |