Physical Properties | | | |
Molecular Weight: 377.871 g/mol | logS: -6.82351 | SlogP: 5.0675 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0270138 | Sterimol/B1: 3.16902 | Sterimol/B2: 4.14566 | Sterimol/B3: 4.19977 |
Sterimol/B4: 5.21157 | Sterimol/L: 22.5584 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 658.529 | Positive charged surface: 383.947 | Negative charged surface: 274.582 | Volume: 339.125 |
Hydrophobic surface: 565.75 | Hydrophilic surface: 92.779 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |