Physical Properties | | | |
Molecular Weight: 418.521 g/mol | logS: -5.2946 | SlogP: 4.54497 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0961259 | Sterimol/B1: 2.37734 | Sterimol/B2: 3.26616 | Sterimol/B3: 5.68793 |
Sterimol/B4: 6.58766 | Sterimol/L: 18.6252 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 663.058 | Positive charged surface: 390.396 | Negative charged surface: 270.595 | Volume: 395.625 |
Hydrophobic surface: 535.151 | Hydrophilic surface: 127.907 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |