Physical Properties | | | |
Molecular Weight: 414.486 g/mol | logS: -5.87577 | SlogP: 3.48062 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0318014 | Sterimol/B1: 2.55704 | Sterimol/B2: 3.14635 | Sterimol/B3: 4.5885 |
Sterimol/B4: 8.57804 | Sterimol/L: 21.371 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 683.662 | Positive charged surface: 387.126 | Negative charged surface: 296.535 | Volume: 376.125 |
Hydrophobic surface: 511.835 | Hydrophilic surface: 171.827 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |