Physical Properties | | | |
Molecular Weight: 411.482 g/mol | logS: -4.0802 | SlogP: 3.4775 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.120885 | Sterimol/B1: 2.56472 | Sterimol/B2: 3.61889 | Sterimol/B3: 6.06938 |
Sterimol/B4: 11.0005 | Sterimol/L: 16.554 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 691.859 | Positive charged surface: 424.439 | Negative charged surface: 267.42 | Volume: 375.25 |
Hydrophobic surface: 534.763 | Hydrophilic surface: 157.096 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |