Physical Properties | | | |
Molecular Weight: 375.488 g/mol | logS: -3.81398 | SlogP: 2.811 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0497095 | Sterimol/B1: 2.78458 | Sterimol/B2: 3.27866 | Sterimol/B3: 4.70491 |
Sterimol/B4: 6.27993 | Sterimol/L: 20.6463 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 666.047 | Positive charged surface: 483.339 | Negative charged surface: 182.708 | Volume: 375 |
Hydrophobic surface: 611.586 | Hydrophilic surface: 54.461 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |